ea0041gp220 | Thyroid Cancer | ECE2016
Chung Yun Jae
, Jeon Min Ji
, Chung Sung Min
, Kim Deokhoon
, Kwon Hyemi
, Kim Won Gu
, Shong Young Kee
, Song Dong Eun
, Kim Won Bae
Background: Anaplastic thyroid carcinoma (ATC) is the most aggressive type of thyroid cancer and has no effective therapy. Due to its dismal prognosis, it is vital to understand the genetic alterations of ATC and identify effective molecular targets. We performed targeted next-generation sequencing to investigate the mutational profile of ATC using a massive parallel sequencing approach.Methods: DNA from formalin-fixed, paraffin-embedded archival samples...